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KMID : 0380620170490060710
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Korean Journal of Food Science and Technology
2017 Volume.49 No. 6 p.710 ~ p.713
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Anti-inflammatory and anti-atopic effects of corn silk (Zea mays L.) ethanol extracts
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Kim Hyun-Young
Lee Mi-Ja
Seo Woo-Duck
Choi Sik-Won
Kim Sun-Lim
Jung Gun-Ho
Kang Hyeon-Jung
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Abstract
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This study evaluates the ability of corn silk (Zea mays L.) extract to function as a natural anti-inflammatory and anti-atopic therapeutic agent. The anti-inflammatory effects of corn silk were evaluated by measuring the inhibitory activities of nitric oxide (NO) and production of tumor necrosis factor-α (TNF-α). Anti-atopic effects were assessed by measuring the repression of thymus and activation-regulated chemokine (TARC). These results indicated that NICS-1 (corn silk ethanol extract) and NICS-3 (high maysin corn silk ethanol extract) functioned as anti-inflammatory agents by down-regulating LPS-induced NO and TNF-α. Additionally, two extracts showed weak repression of TARC expression levels in tumor necrosis factor TNF-α plus IFN-γ induced HaCaT cells, respectively. These results suggest that corn silk extracts have anti-inflammatory and anti-atopic activities, and thus have the potential to reduce and alleviate the symptoms associated with atopic dermatitis.
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KEYWORD
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corn silk, anti-inflammatory, anti-atopic
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